Quinolines and derivatives
Medchemexpress LLC 5-Amino-8-hydroxyquinoline | 13207-66-4 | 160.18 | 100 MG
5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active, non-competitive 20S proteasome inhibitor. It has the ability to inhibit NF-κB activity and induce the death of cancer cells, while exhibiting low cytotoxicity towards normal hematopoietic cells. This compound can be utilized for research related to cancer, particularly leukemia.
- Orally active.
- Functions as a non-competitive 20S proteasome inhibitor.
- Inhibits NF-κB activity.
- Induces cancer cell death.
- Shows low cytotoxicity towards normal hematopoietic cells.
- Can be used for cancer research, including leukemia.
Medchemexpress LLC RU.521 500mg | 2262452-06-0 | 500 MG
RU.521 is a potent, selective small-molecule inhibitor of cyclic GMP-AMP synthase (cGAS) provided as a solid research chemical for in vitro and in vivo pathway and interferon-response studies.
- Potent and selective cGAS inhibitor.
- High purity suitable for research use.
- Chemical formula C19H12Cl2N4O3; molecular weight 415.23.
- Soluble in DMSO; in vivo formulation examples are reported.
- Available in multiple package sizes, including a 500 mg pack.
- Store powder at -20°C for long-term stability; in solvent storage recommendations provided.
Apexbio Technology LLC Ethidium bromide 1239-45-8 500mg
Ethidium bromide (CAS 1239-45-8) is a small-molecule fluorescent dye widely utilized in molecular biology for nucleic acid visualization It intercalates between the base pairs of double-stranded DNA or RNA resulting in enhanced fluorescence upon binding With an excitation spectrum between 300 360 nm and an emission maximum at 590 nm ethidium bromide is commonly used to stain nucleic acids during agarose gel electrophoresis This property facilitates the detection and analysis of DNA and RNA in applications such as gene expression studies and nucleic acid quantification supporting a broad range of experimental workflows in genomics and molecular diagnostics
Medchemexpress LLC Propidium Iodide | 25535-16-4 | 99.7% | 500 MG
Propidium Iodide | 25535-16-4 | 99.7% | 500 MG
Medchemexpress LLC Propidium Iodide | 25535-16-4 | 99.7% | 50 MG
Propidium Iodide (PI) is a nuclear staining agent that stains DNA. It is an analogue of ethidine bromide, which emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. It is commonly used in the detection of apoptosis or necrosis, and is often used in flow cytometry analysis.
- Nuclear staining agent for DNA.
- Emits red fluorescence upon embedding in double-stranded DNA.
- Cannot pass through living cell membranes, but stains nuclei of cells with damaged membranes.
- Fluorescence wavelength of 493/617 nm, and 536/635 nm after Mosaic with DNA.
- Commonly used in detection of apoptosis or necrosis.
- Often used in flow cytometry analysis.
- Can be used in cell cycle and cell viability assays.
Medchemexpress LLC Act-1004-1239 | 2178049-58-4 | 98.8% | C27H28F2N6O3 | 10MG
ACT-1004-1239 is a potent, selective, orally available CXCR7 (ACKR3) antagonist developed as a first-in-class compound. It exhibits low nanomolar potency and has shown immunomodulatory and promyelinating effects in preclinical models and early clinical research.
- Potent CXCR7 antagonism with IC50 3.2 nM.
- Orally bioavailable compound suitable for systemic dosing.
- Demonstrated immunomodulatory and promyelinating activity in vivo.
- High chemical purity and solid, stable formulation for storage.
- Compatible with in vitro and in vivo pharmacology studies.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
Medchemexpress LLC Chelerythrine chloride | 3895-92-9 | 99.1% | 100 MG
Chelerythrine chloride is a cell-permeable benzophenanthridine alkaloid used as a research reagent to inhibit protein kinase C (PKC) and to probe apoptosis and Bcl-2 family interactions in cell-based and biochemical assays.
- Potent PKC inhibitor (IC50 660 nM).
- Inhibits Bcl-XL-Bak BH3 peptide binding (IC50 ~1.5 μM).
- High reported purity (99.11%).
- Supplied as a solid powder; easily soluble in DMSO (4.35 mg/mL).
- Recommended storage: 4°C sealed; in solution store at -80°C for up to 6 months.
Medchemexpress LLC Dimidium bromide | 518-67-2 | 98.6% | 1 G
Dimidium bromide is a biochemical reagent used in life science research as a biological material or organic compound.
- Solid appearance
- Pale purple to purple color
- Store at room temperature, sealed, away from moisture and light
- In solvent, store at -80°C for 1 year or -20°C for 6 months
- Soluble in DMSO (125 mg/mL)
Medchemexpress LLC Chelerythrine chloride | 3895-92-9 | 99.1% | 25MG
Chelerythrine chloride | 3895-92-9 | 99.1% | 25MG